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KMID : 1094720160210020314
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Biotechnology and Bioprocess Engineering
2016 Volume.21 No. 2 p.314 ~ p.320
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Xanthine biosensor based on XO/AuNP/PtNP/MWCNT hybrid nanocomposite modified GCPE
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Cevik Serdar
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Abstract
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A new xanthine (X) biosensors based on a hybrid nanocomposite containing multi-walled carbon nanotubes (MWCNT), Pt nanoparticles (PtNP) and gold nanoparticle (AuNP) was presented. X biosensor was fabricated by dropping AuNP/PtNP/MWCNT onto xanthine oxidase (XO) modified glassy carbon paste electrode (GCPE). Resulted XO/AuNP/PtNP/MWCNT/GCPE biosensor showed two linearity between 2.0 and 50 μM and 0.25 and 6.0 mM for X. RSD value was calculated as 2.46 (n = 5). Finally, the biosensor was applied to the X detection in synthetic serum samples and good recovery value was obtained.
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KEYWORD
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hybrid nanocomposite, gold nanoparticle, Pt nanoparticles, multi-walled carbon nanotubes, xanthine biosensor
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